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LncRNAs, typically exceeding 200 nucleotides, not only regulate gene activity near their synthesis site or at distant locations but also act as “sponges” to bind miRNAs, thereby inhibiting their ability to regulate other target mRNAs

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On the basis of such standard assays, different isoforms are hereinafter referred to as ‘enzymatically active or inactive glutaredoxins’ for the sake of simplicity (without excluding the possibility that inactive isoforms might actually catalyse other reactions with specialized substrates in vivo )