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2,76 The type 3 5′-deiodinase enzyme also degrades reverse T3 into inactive diiodothyronine

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A clinical trial investigating the effects of curcumin on psychological status, inflammation, and oxidative damage markers in patients with type 2 diabetes and coronary heart disease (IRCT20170513033941N63) revealed reduced malondialdehyde (MDA) levels, increased total antioxidant capacity and glutathione (GSH) levels, and upregulated PPAR-γ gene expression in these patients (111)