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52 GLP-1R agonists also regulate gene expression related to β cell maturation (pancreatic and duodenal homeobox 1, MAF bZIP transcription factor A, and neuronal differentiation 1, upregulated) and to apoptosis (thioredoxin interacting protein, CASP3, and B-cell lymphoma 2 (Bcl-2) associated X, apoptosis regulator, downregulated)