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[DOI] [PubMed] [Google Scholar] 112.Shi F, Chowdhury R, Sofianopoulou E, Koulman A, Sun L, Steur M, Aleksandrova K, Dahm CC, Schulze MB, van der Schouw YT, et al

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The therapeutic targeting of glucose metabolism has been validated in preclinical in vitro models using 2-deoxy-D-glucose (2DG), a synthetic non-metabolizable glucose analog that acts as a hexokinase 2 (HK2) inhibitor, targeting one of the rate-limiting enzymes in glycolysis (60)