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Frontiers | Alcohol-Induced Neuroinflammatory Response and Mitochondrial Dysfunction on Aging and Alzheimer's Disease

Even though betaine may be linked to TMAO production (Figure 2 and [37]), the single ingestion of 1760 mg betaine did not lead to an increase in urinary TMAO excretion in an experimental model [41]

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ROS are produced more often under stress, which causes oxidative damage to neurons