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A reasonable candidate is someone who: Is already following a structured, clinician-supervised nutrition and activity plan Has a documented B12 deficiency or a condition that impairs B12 absorption Cannot tolerate GLP-1 medications, or is not a candidate for them Declines prescription pharmacotherapy and wants a non-stimulant, non-surgical adjunct Understands — because the clinician has said so plainly — that the injection is a supporting player A poor candidate is someone who wants the shot instead of the program

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10.1186/s12986-022-00653-9 171 ZhouQ.HuangZ.-G.ZhuX.-J.XieZ.-H.YaoT.-F.WangY.-H.et al (2018)