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112 Similarly, the oral administration of Jamun leaves, stem bark, root, or seeds extracted in methanol (except seeds) was found to be nontoxic up to 2,000 mg/kg in rats, and the administration of 100 and 500 mg/kg body weight aqueous leaf extract for 30 days in rats in drinking water was nontoxic as no significant changes were observed in the organ or body weights of male Wistar rats