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However, due to the side effects reported when using the standard prophylactic medication (antiepileptic drugs, calcium channel inhibitors) [38,39] or abortive therapy, the discovery of substances with a more gentle effect and better tolerance is still required, i.e., causing less side effects [40]

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Analysis of pulmonary heme oxygenase-1 and nitric oxide synthase alterations in experimental hepatopulmonary syndrome