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Under basal homeostatic conditions, Nrf2 is sequestered in the cytoplasm through its interaction with the adaptor protein KEAP1 (Kelch-like ECH-associated protein 1), which targets Nrf2 for ubiquitination and subsequent proteasomal degradation

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Product Type:1667 Capsules

Additionally, combination therapies targeting ferroptosis with conventional DN treatments (e.g., SGLT2 inhibitors and RAS blockers) are understudied