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Results showed significant amelioration of arthritis symptoms in ASPS-FMT recipients, whereas model-FMT or ABX controls showed limited improvement, suggesting that “the ASPS-associated microbial configuration possesses a transferable therapeutic effect.” Rescue (Sufficiency Verification of Key Mediator via Exogenous Supplementation): To test if GGC is the key mediator, the authors exogenously supplemented GGC in CIA model mice (100 mg/kg/day, oral

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This can include changes in sleep, reduced energy levels, increased or decreased appetite, and decreased ability to concentrate