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It was reported that eIF4G2 (one of three isoforms in eIF4F) is co-expressed with MOR in small DRG neurons, the expression of which in the ipsilateral L4 DRG of mice increased over time after SNL, reducing the expression of MOR [119], which suggests that eIF4G2 may promote NP by negatively regulating the expression of MOR in injury-related DRG neurons [119]