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Additionally, the findings are based on a single case and may not be generalizable to other individuals, highlighting the need for further research in a larger cohort

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A more recent concern has arisen from reports that the presence of unmetabolised folic acid in plasma in elderly people with low vitamin B 12 status is associated with worse cognitive performance compared to those with low B 12 status and no detectable folic acid in the circulation (Reference Morris, Jacques and Rosenberg109)