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Adipogenesis and metabolic health | Nature Reviews Molecular Cell Biology

37 More research is needed, but three small studies of a multidisciplinary approach that includes physical, occupational, and cognitive behavior therapy have shown reduced anxiety, depression, catastrophizing, and kinesiophobia (fear of pain due to movement), with improved physical function and self-efficacy in treated patients

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Materials and methods Intervertebral disc specimens Normal intervertebral disc tissues were collected from five patients: four males and one female