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Melanoma MD Anderson Multidisciplinary Care Discussion Panel: Medical Oncology

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They reported that 5-methylthioadenosine, cystathione, cysteine, cysteine sulphinic acid and methionine decreased in the resistant cells compared to the sensitive cells, while alanine, aspartate, reduced GSH, S -formyl-l-methionine and pyruvate were increased in resistant cells [97]