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Gpx33-GFP was not readily detectable, consistent with previous RNAseq studies showing it is expressed at a low level [3,62]

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In mouse experiments, Klevay and Viestenz (116) observed that copper-deficient rats exhibited a range of electrocardiographic abnormalities, including ST-segment depression spanning one-third to one-half of the RR interval, bundle-branch block with R-wave heights and widths three times the normal values, Q-waves, and second- and third-degree heart block