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(1) Histone Methylation: The addition of methyl groups ( CH 3 ) to histone proteins, primarily at lysine ( K ) and arginine ( R ) residues, by histone methyltransferases ( HMTs )

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Following the indicated treatment, cells were subjected to a 10-minute incubation with 5 µM MitoSOX at 37 °C, subsequent to which fluorescence intensity was assessed using a microplate reader (TECAN) at absorption/emission peaks approximately around 396/610 nm