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After reactions started, the catalytic products’ absorbance was recorded every 30 s for 20 min to reflect their initial velocity

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Book an appointment if: Over-the-counter creams show no results after 12 weeks Pigmentation is spreading or darkening You want to start oral tranexamic acid or prescription-strength topicals You are considering chemical peels, lasers, or microneedling Melasma is affecting your confidence or mental health You have other skin conditions, like rosacea or post-inflammatory hyperpigmentation, that are complicating treatment Final Word Melasma treatment has advanced significantly in the past five years