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Foaming and surface denaturation of peptides during reconstitution

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More specifically, aberrant plasma cells exhibit an extraordinary ability to interact with bone marrow mesenchymal stem cells, osteoblasts, osteoclasts, endothelial cells, adipocytes, and the immune system to induce a state of immune suppression while promoting bone marrow remodeling to obtain the best conditions favoring aberrant plasma cell expansion and drug resistance (Pojero et al., 2019)