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[576] showed that the activity of 9- lipoxygenase on linolenic acid produces 10-oxo-11-phytotenoic acid as well as 12- and 14-carbon cyclopente( a )nones, which are named “death acids” that regulate the expression of genes related to defense and that promote cytotoxicity

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This approach holds promise for the development of more precise and effective therapeutics targeting GPCRs