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3 Results Our search identified 2,124 potential studies, of which 1,559 were screened based on the title and abstract, resulting in 81 full-text articles assessed for eligibility

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It has been shown that HTX-3 nanoparticles, a derivative of HTX conjugated to caffeic acid skeletons, can enhance BBB penetration, accelerate metabolism, and prolong brain retention in murine models [96]