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In humans, CPT1 exists in three isoforms: the liver isoform (CPT1A), the muscle isoform (CPT1B), and the brain isoform (CPT1C) (Lane et al

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proposed to replace the traditional nano-QSAR model with an approach called Structure–Activity Prediction Networks (SAPNets), claiming it can effectively link NP structure with their toxicity through a series of layers built from nodes that correspond to predictive “meta-models” developed with machine learning techniques as well as Artificial Intelligence (Rybinska-Fryca et al., 2020)