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Subsequently, local refinement and local CTF refinement were performed with a mask generated from the reconstructed volume around the 5 f axis, producing a final density map with a resolution of 3.90 Å

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Because VEGFRs and FGFRs, targets of lenvatinib, exert various physiological effects partly through the mTOR signaling (Liu et al., 2021), it is plausible that lenvatinib also inhibits protein synthesis via the mTOR pathway