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Trigeminal neuralgia (TN) is facial pain attributable to a lesion or disease of the trigeminal nerve, affecting at least one branch, and is characterised by brief pain attacks described as sharp, stabbing, or electric shock–like

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When stratified by administration route, the average percentage reductions were: Intramuscular (IM): −48.3% Sublingual: −30.7% Oral: −30.3% These results suggest that IM administration leads the most pronounced homocysteine reduction, however, sublingual and oral routes also demonstrate clinically relevant effects