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The persistent effect on re-pigmentation of vitiligo after the injections of antioxidants and the increasing effect with a repeated course, support the theory of involvement of oxidative stress in the pathogenesis of vitiligo

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In detail, the last seven amino acids of the Gα s -α5 helix connect with R139 3.50 , A142 3.53 , and I143 3.54 of TM3, L236 5.65 of TM5, K308 6.30 , A307 6.29 and R310 6.32 of TM6, and N374 8.47 at the TM7–Helix8 hinge in CCK1R (Fig