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The half-life of a drug can be determined using the following equation: t 1/2 = (0.7 times V d ) / Cl Therefore, t 1/2 = (0.7 times 40L) / 2.0 L/hour, and t 1/2 = 14 hours

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[DOI] [PubMed] [Google Scholar] 11.Braig M, Schmitt CA