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The NCI risk group classification for B-ALL stratifies risk according to age and white blood cell (WBC) count, as follows:[3] Standard risk: WBC count less than 50,000/μL and age 1 to younger than 10 years

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Methylation Methyltransferases add methyl (CH 3 ) groups transferred from S-adenosylmethionine (SAM) to bioactive drug substrates or drug metabolite