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Although the precise molecular mechanism by which ellagic acid modulates pro-inflammatory cytokine activity remains to be fully elucidated, it is hypothesized that this polyphenolic compound exerts its anti-inflammatory effects primarily through direct inhibition of the NF-κB signaling pathway

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Besides burn sensation or inflammation at the injection site (4%) and drowsiness/confusion (1%), nausea, and vomiting were observed in 2% of the patients (Rasamison et al