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In the first step, catalase reacts with hydrogen peroxide in its ferric state, forming a Compound I complex and converting the ferric state to the ferrous state

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For example, CCl 4 -inhibited antioxidant enzyme activities (eg, from superoxide dismutase, catalase, glutathione peroxidase, and glutathione-S-transferase) could be markedly reversed using an extract of the herb Euphorbia dracunculoides in rat liver tissues [97]