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Contrarily, in BPC 157-treated rats, we noted a focal edema of interlobar septe, a diffuse occurrence of 5–10 necrotic cells/HPF, a focal occurrence of 11–16 necrotic cells/HPF, up to one focus of hemorrhage, and up to seven foci of fat necrosis, mostly in the pancreatic tail, while the pancreatic head was not affected with fat necrosis