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These mutations are often, but not always, detected in conjunction with activation of the Unfolded Protein Response (UPR) pathway, which has also been reported in the alveolar epithelial cells of IPF patients carrying the SFTPC L188Q mutation (Tanjore et al., 2012

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Amount:3ml

This increases the risk of neural tube defects, such as spina bifida, developing in the unborn baby