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MAOI monoamine oxidase inhibitor, NDRI norepinephrine-dopamine reuptake inhibitor, NMDAR N-methyl-D-aspartate receptor, RCT randomized controlled trial, SNRI serotonin-norepinephrine reuptake inhibitor, SSRI selective serotonin reuptake inhibitor a See Table 5 for randomized controlled trial citations, study designs, and sample description Not included: MDMA/ecstasy co-ingestion from cross-sectional studies (Copeland et al