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Side Effects Of IV Glutathione Therapy Glutathione is considered safe generally, however, the following have been documented as possible side effects: Allergic reactions Temporary abdominal discomfort (bloating, pain, etc) Introduction of harmful microorganisms or use of contaminated infusions leading to serious infections (when done by non-medical personnel) Kidney stones, Goitre (when larger than recommended doses are used) *Note that : effects of glutathione and other antioxidants are slower in alcohol and cigarette users