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Ingredients like green tea extract can cause liver inflammation, which is exacerbated by alcohol.39 Recreational drugs generally increase either dopamine, serotonin, or glutamate (inhibiting GABA), so adding nootropic ingredients that do the same thing can lead to side effects like tremors or worse

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Laboratory research record on NAD+ [PMID: 31208524] PubMed laboratory record discussing NAD+ in a research context