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Furthermore, emerging studies have confirmed that there exists a mutually reinforcing positive feedback mechanism between oxidative stress and inflammation, where ROS and mitochondrial damage products are good activators of inflammatory responses (46, 47)
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Therefore, it is important to develop new strategies to prevent, reduce, or treat UV radiation damage using natural products: in this view, leaves possess a great potential for the pharmacological and cosmetic industry to be a candidate as a natural source for obtaining extracts with strong UV protection effect (347, 348)