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Alternatively, for patients who prefer oral treatment and have sufficient absorption, high-dose oral cyanocobalamin (1-2 mg daily) may be considered, although its effectiveness in pernicious anemia is still debated [22]

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The canonical pathway of adipocyte lipolysis is catalyzed by three main lipases: patatin-like phospholipase domain containing-2 (PNPLA2)/adipocyte triglyceride lipase (ATGL) (17), hormone sensitive lipase (HSL) (18), and monoacylglycerol lipase (MGL) (19)