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The liberated NF-κB then translocates to the nucleus, where it binds to the promoter regions of target genes, initiating the transcription of inflammation-related genes such as the inflammatory cytokines IL-1β, IL-6, and TNF-α, and inflammatory enzymes like COX-2 and Inos
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56 Likewise, RSV infection of A549 epithelial cell lines showed the inhibitory effects of N-acetylcysteine on virus-induced chemokine expression and DNA-binding activity of NF-κB subunits of p50 and p65
Carnitine is a naturally occurring amino acid derivative that plays a crucial role in the metabolism of fat