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[PubMed] [Google Scholar] 40.Lyons SD, Sant ME, Christopherson RI: Cytotoxic mechanisms of glutamine antagonists in mouse L1210 leukemia

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Moreover, lapatinib-resistant BT-474 breast cancer cells have shown to be dependent on enhanced glycolytic enzyme (Aldolase A) activity which reversibly forms glyceraldehyde 3-phosphate from fructose-1,6-bisphosphate, thus are susceptible to glycolysis inhibition [291]