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Urea synthesis serves to remove from the body (by excreting it in the urine) the toxic ammonia that is generated during various metabolic reactions (including the breakdown of proteins)

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beyond that trial and the halted Phase 2 lipodystrophy study, there are no completed human trials measuring body composition, strength, or long-term safety outcomes, so evidence for bodybuilding-related benefit claims remains preliminary and largely extrapolated from the hormone's known biology rather than from direct testing of CJC-1295