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Delaying the homotopic transplantation of embryonic cells into the adult mouse motor cortex by one week after aspiration injury significantly improved graft outcomes, including increased vascularization, enhanced cell proliferation and survival, and greater density of tNs axonal projections, and this was accompanied by an increase in the number of astrocytes, microglia, OLs, and CD45 + cells, compared to the acute transplantation (Péron et al., 2017
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4.3 Clinical implications: balancing benefits and risks in practice Healthcare providers should implement targeted strategies to address nutraceutical-related risks, focusing on comprehensive reviews of nutraceutical-drug interactions and the discontinuation of non-essential supplements in high-risk populations, such as the elderly or those undergoing polypharmacy (102)