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For instance, assessing the levels of activity of particular antioxidant enzymes or markers of oxidative damage (such as lipid peroxidation or protein oxidation) can help determine disease progression, treatment response, or even identify specific pathological conditions linked to oxidative stress
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(2011) published that, beyond hypermethylation, chromatin remodeling by a combinatorial complex between estrogen receptor (ER) and endothelial nitric oxide synthase (eNOS) also represses transcription of prognostic genes that are down-regulated in PCa, such as GSTP1
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